Active substance: Yohimbine hydrochloride
Tradenames: Aphrodyne, Viritab, Yocon, Tohimex
Yohimbine hydrochloride is a synthetic copy of the alkaloid found in the yohimbine extract. It is an antagonist of alpha-2 adrenergic receptors. Is a prescription drug in many countries, being used to increase blood pressure, dilate pupils or for treating impotence and stimulate fat burning.
To understand how Yohimbine works you have to know that adrenergic lipolysis in adipose human tissue takes place in a dual mode being initiated by the adrenoceptors. Activation of beta-1 , beta-2 and beta-3 receptors leads to increased lipolysis, whereas alpha-2 receptor activation leads to a decrease in lipolysis. Fat cells appear to be the only cells in the body that respond in two opposing ways to the stimulation of the adrenoceptors. By blocking alpha-2 receptors, yohimbine can stimulate lipolysis.
Typical dose to stimulate fat burning is 15-20 mg, which is administered in the morning on an empty stomach. Yohimbine levels in the body accumulates over time, so it may take several weeks for the effects to show. Studies have shown that the body can tolerate up to 40 mg without any side effects. If side effects occur this are: increased heart rate, sweating, nervousness, tremors, irritability, headache, dizziness. These side effects are closely related to the dose used so it is not recommended to use more with thehope to burn fat faster.
Altogether, the effects of yohimbine HCL are not extraordinary. It works but a dramatic fat loss is unlikely to happen. It's a good idea to take yohimbine HCL on an empty stomach; taking it after meals can inhibit its effect.
Bodybuilders and atheletes will get much stronger effects using Clenbuterol or ephedrine, but the risks associated with these products are much higher. Yohimbine hydrochloride is used by those who want a little boost for fat loss, but don't want to tale many risks.